Colistimethate 2 MIU (Million International Units) is a polymyxin-class antibiotic primarily used as a critical, last-resort treatment for severe, multidrug-resistant Gram-negative bacterial infections. It destroys the bacteria's cell membrane and is typically reserved for hospitalized or critically ill patients when other antibiotics have failed.
Primary Clinical Uses
- Severe Systemic Infections: Used to treat infections of the bloodstream, abdomen, and urinary tract caused by highly resistant pathogens like Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae.
- Respiratory Infections: Frequently administered in intensive care settings for severe pneumonia, or inhaled to manage chronic chest infections and airway colonization in patients with conditions like cystic fibrosis.
- Hospital-Acquired Infections: Often utilized in neonatal, pediatric, and adult intensive care units to fight XDR (extensively drug-resistant) hospital-acquired infections.
